Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11727641 | 0.86 | GSR (0.48) | CYP1A2CYP2D6TSHRTP53THPO | |
| SCHEMBL11818226 | 0.85 | MAPT (0.48) | KDM4EALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL11873000 | 0.82 | MAPT (0.46) | KDM4EALDH1A1CYP1A2CYP2D6TSHR | |
| SCHEMBL11862026 | 0.82 | CYP1A2 (0.46) | KDM4ECYP1A2CYP2D6TSHRTP53 | |
| Hydrochloric Acid SCHEMBL11862809 | 0.81 | MEN1 (0.46) | KDM4ECYP1A2CYP2D6TSHRTP53 | |
| Hydrochloric Acid SCHEMBL11678026 | 0.81 | MAPT (0.56) | KDM4EUSP2ALDH1A1CYP1A2TSHR | |
| SCHEMBL11813095 | 0.79 | GSK3B (0.44) | KDM4EALDH1A1TP53MAPTNPC1 | |
| SCHEMBL11794930 | 0.78 | ALDH1A1 (0.45) | KDM4EUSP2ALDH1A1TSHRTP53 | |
| SCHEMBL11732533 | 0.78 | THRA (0.38) | CYP1A2CYP2D6TSHRTP53THPO | |
| SCHEMBL11730430 | 0.78 | CTNNB1 (0.36) | KDM4EALDH1A1TSHRMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |