Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 2/20 | 0.48 |
| ▸ | THRA | P10827 | 12/20 | 0.43 |
| ▸ | THRB | P10828 | 10/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11862026 | 0.90 | CYP1A2 (0.46) | GSRTHRATHRBTP53CYP1A2 | |
| Hydrochloric Acid SCHEMBL11862809 | 0.89 | MEN1 (0.46) | GSRTHRATHRBTP53CYP1A2 | |
| SCHEMBL11869377 | 0.86 | KDM4E (0.45) | GSRTHRATHRBTP53CYP1A2 | |
| SCHEMBL11732533 | 0.85 | THRA (0.38) | THRATHRBTP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL11734361 | 0.83 | MAOA (0.37) | GSRTHRATHRBTP53CYP1A2 | |
| SCHEMBL11872995 | 0.82 | THRA (0.53) | THRATHRBCYP1A2CYP2D6 | |
| SCHEMBL11730448 | 0.80 | L3MBTL1 (0.43) | THRATHRBTP53CYP1A2CYP2D6 | |
| SCHEMBL11730430 | 0.80 | CTNNB1 (0.36) | TSHRMAPTSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11862770 | 0.79 | L3MBTL1 (0.44) | THRATHRBTP53CYP1A2CYP2D6 | |
| SCHEMBL11866455 | 0.79 | L3MBTL1 (0.39) | THRATHRBTP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008240-A | VIRICIDE | RICHARDSON-MERRELL INC. (US) | 1977-02-15 | — | — | US | disclosed |