SCHEMBL11869488

SCHEMBL11869488

CCC1Cc2c(C)ccc(C)c2C1=O

nearest known ligand 0.46

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 8/20 0.46
MAOB P27338 3/20 0.38
POLL Q9UGP5 1/20 0.36
HSP90AB1 P08238 1/20 0.36
ACHE P22303 1/20 0.36
TBXA2R P21731 1/20 0.32
AKT1 P31749 1/20 0.32
AKT2 P31751 1/20 0.32
AKT3 Q9Y243 1/20 0.32
AADAT Q8N5Z0 1/20 0.32
PDE9A O76083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1022897 0.86 MAOA (0.42) MAOAMAOBPOLLHSP90AB1ACHE
SCHEMBL11874566 0.86 MAOA (0.60) MAOAMAOBPOLLHSP90AB1ACHE
SCHEMBL11078273 0.80 MAOA (0.39) MAOAMAOBPOLLACHE
SCHEMBL1023551 0.77 MAOA (0.36) MAOAMAOBACHE
SCHEMBL5952896 0.75 MAOA (0.37) MAOAMAOBHSP90AB1
SCHEMBL5952264 0.75 HTR1A (0.38) MAOAMAOBHSP90AB1
SCHEMBL7627859 0.75 ACHE (0.62) MAOAACHEAADAT
SCHEMBL31693572 0.75 ACHE (0.56) MAOAMAOBPOLLACHEAKT1
SCHEMBL2046109 0.75 ACHE (0.56) MAOAMAOBPOLLACHEAKT1
SCHEMBL18264394 0.73 MAOA (0.40) MAOAMAOBPOLLACHEAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3944679-A Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) 1976-03-16 US claimed
US-3944679-A Process for imparting a coumarin-like aroma and flavor to tobacco, foods and drinks THE JAPAN TOBACCO & SALT PUBLIC CORPORATION (JA) 1976-03-16 US disclosed