Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOX | P28300 | 1/20 | 0.67 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.67 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.67 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 10/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861844 | 0.82 | MAPT (0.49) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL1086022 | 0.80 | LOX (1.00) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL11861507 | 0.79 | LOX (0.43) | LOXLOXL3LOXL4LOXL2CYP1A2 | |
| SCHEMBL8930590 | 0.77 | CES2 (0.65) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL6573304 | 0.77 | LMNA (0.55) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL17290688 | 0.76 | LOX (0.63) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL9381720 | 0.76 | LOX (0.58) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL371374 | 0.75 | LOX (0.61) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL17291113 | 0.74 | LOX (0.56) | LOXLOXL3LOXL4LOXL2ALDH1A1 | |
| SCHEMBL418870 | 0.72 | HTT (0.50) | LOXLOXL3LOXL4LOXL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000156-A | HYDROGENATION, METHYLATION WITH PARAFORMALDEHYDE | AGFA-GEVAERT N.V. (BE) | 1976-12-28 | — | — | US | disclosed |