Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.47 |
| ▸ | LOXL4 | Q96JB6 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | CES2 | O00748 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418870 | 0.83 | HTT (0.50) | LMNAHTTPKMMAPTCYP2C9 | |
| Water SCHEMBL6895357 | 0.81 | LMNA (0.71) | LMNAHTTPKMMAPTCYP2C9 | |
| SCHEMBL419792 | 0.79 | MAPT (0.61) | LMNAHTTPKMMAPTCYP2C9 | |
| SCHEMBL11869646 | 0.77 | LOX (0.67) | LMNAHTTPKMMAPTALDH1A1 | |
| SCHEMBL28708842 | 0.74 | LMNA (0.75) | LMNAHTTPKMMAPTCYP2C9 | |
| SCHEMBL22670234 | 0.72 | HTT (0.55) | LMNAHTTPKMMAPTCYP2C9 | |
| SCHEMBL3259546 | 0.72 | ALDH1A1 (0.49) | LMNAHTTPKMMAPTCYP2C9 | |
| SCHEMBL11376494 | 0.71 | MT-CO2 (0.46) | LMNAHTTPKMMAPTALDH1A1 | |
| SCHEMBL420936 | 0.71 | NPC1 (0.47) | LMNAMAPTALDH1A1KDM4EMEN1 | |
| SCHEMBL12309402 | 0.71 | HTT (0.69) | LMNAHTTPKMMAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408918-A2 | HAIR COLOURING COMPOSITIONS AND THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003009822-A2 | HAIR COLOURING COMPOSITIONS AND THEIR USE | THE PROCTER & GAMBLE COMPANY (US) | 2003-02-06 | — | — | WO | disclosed |