Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.66 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 4/20 | 0.51 |
| ▸ | TEK | Q02763 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881074 | 0.90 | LMNA (0.65) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL31547327 | 0.89 | LMNA (0.82) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL166352 | 0.89 | LMNA (0.82) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL31547342 | 0.89 | LMNA (0.82) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL3988034 | 0.89 | LMNA (0.82) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL30596374 | 0.89 | LMNA (0.58) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL24359553 | 0.88 | LMNA (0.66) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL14375419 | 0.88 | LMNA (0.66) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| Fenbendazole SCHEMBL28228589 | 0.88 | LMNA (0.80) | LMNACYP1A2MEN1KMT2ANR1I2 | |
| SCHEMBL11879658 | 0.88 | LMNA (0.66) | LMNACYP1A2MEN1KMT2ANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |