Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.49 |
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11865791 | 0.99 | CNR2 (0.47) | CNR2CNR1HPGDRAD52 | |
| SCHEMBL11859783 | 0.93 | RAD52 (0.44) | CNR2CNR1HPGDRAD52 | |
| SCHEMBL11865693 | 0.91 | PTGS2 (0.47) | CNR2CNR1RAD52 | |
| SCHEMBL11858506 | 0.85 | CNR2 (0.56) | CNR2CNR1RAD52 | |
| SCHEMBL11870710 | 0.84 | CNR2 (0.54) | CNR2CNR1RAD52 | |
| SCHEMBL11861062 | 0.83 | CNR2 (0.54) | CNR2CNR1RAD52 | |
| SCHEMBL11859533 | 0.82 | RAD52 (0.47) | CNR2CNR1HPGDRAD52 | |
| SCHEMBL11864104 | 0.82 | RAD52 (0.57) | CNR2CNR1HPGDRAD52 | |
| Hydrochloric Acid SCHEMBL11861513 | 0.81 | RAD52 (0.57) | CNR2CNR1HPGDRAD52 | |
| SCHEMBL11863026 | 0.81 | KMT2A (0.53) | CNR2CNR1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3940418-A | Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds | G. D. SEARLE & CO. (US) | 1976-02-24 | — | — | US | disclosed |