Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 3/20 | 0.34 |
| ▸ | BLM | P54132 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861562 | 0.86 | ADORA2A (0.45) | ADORA2AADORA1MERTKADORA2BADORA3 | |
| SCHEMBL11158436 | 0.84 | ADORA3 (0.46) | ADORA2AADORA1ADORA2BADORA3ALDH1A1 | |
| SCHEMBL11866327 | 0.84 | MAPT (0.45) | ADORA2AADORA1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL11166830 | 0.83 | MAPT (0.43) | MAPTLMNA | |
| SCHEMBL11861998 | 0.83 | ADORA2A (0.41) | ADORA2AADORA1MERTKCNR2 | |
| SCHEMBL11867581 | 0.82 | ADORA2A (0.43) | ADORA2AADORA1MERTKADORA2BADORA3 | |
| SCHEMBL11859813 | 0.81 | CHEK1 (0.42) | ADORA2AADORA1ADORA2BADORA3ALDH1A1 | |
| SCHEMBL11861502 | 0.80 | ADORA2A (0.42) | ADORA2AADORA1MERTKADORA2BADORA3 | |
| SCHEMBL11865026 | 0.80 | LMNA (0.37) | MAPTLMNACNR2RORARORC | |
| SCHEMBL11865450 | 0.80 | GRIN1 (0.42) | ADORA1MERTKALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |