Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 11/20 | 0.41 |
| ▸ | PARG | Q86W56 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11861562 | 0.85 | ADORA2A (0.45) | ADORA2AADORA1CNR2MERTK | |
| SCHEMBL11158436 | 0.83 | ADORA3 (0.46) | ADORA2AADORA1 | |
| SCHEMBL11166292 | 0.83 | PTGS2 (0.47) | CNR2PARGKCNH2 | |
| SCHEMBL11866327 | 0.83 | MAPT (0.45) | ADORA2AADORA1 | |
| SCHEMBL11873293 | 0.83 | ADORA2A (0.38) | ADORA2AADORA1CNR2MERTK | |
| SCHEMBL11859813 | 0.82 | CHEK1 (0.42) | ADORA2AADORA1 | |
| SCHEMBL11867581 | 0.82 | ADORA2A (0.43) | ADORA2AADORA1MERTK | |
| SCHEMBL11870097 | 0.80 | PARG (0.38) | CNR2PARGKCNH2 | |
| SCHEMBL11858985 | 0.80 | GRIN1 (0.42) | ADORA1CNR2PARGKCNH2MERTK | |
| SCHEMBL11861502 | 0.79 | ADORA2A (0.42) | ADORA2AADORA1MERTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950526-A | Quinazoline derivatives in pharmaceutical compositions for treating pain and inflammation | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-13 | — | — | US | disclosed |