Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11878957 | 0.88 | CCNT1 (0.31) | CCNT1CDK9MAP3K12 | |
| SCHEMBL11879887 | 0.82 | SIRT6 (0.39) | ALOX15HTTKDM4EALDH1A1LMNA | |
| SCHEMBL11874289 | 0.82 | SIRT6 (0.39) | ALOX15HTTKDM4EALDH1A1LMNA | |
| SCHEMBL10251494 | 0.78 | MEN1 (0.43) | KDM4EALDH1A1PIK3CA | |
| SCHEMBL11872026 | 0.78 | S1PR1 (0.45) | — | |
| SCHEMBL23676503 | 0.77 | ALOX15 (0.54) | CCNT1CDK9ALOX15HTTAAK1 | |
| SCHEMBL20100075 | 0.76 | S1PR1 (0.36) | CCNT1CDK9MAP3K12 | |
| SCHEMBL12724791 | 0.75 | KDM4E (0.53) | CCNT1CDK9AAK1KDM4EALDH1A1 | |
| SCHEMBL24910306 | 0.72 | NR1H2 (0.47) | HSD11B1NR1H2NR1H3ALDH1A1 | |
| SCHEMBL24978830 | 0.72 | KDM4E (0.47) | HSD11B1KDM4EALDH1A1LMNAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987182-A | NOVEL BENZIMIDAZOLES USEFUL AS ANTI-ANDROGENS | SCHERING CORPORATION (US) | 1976-10-19 | — | — | US | claimed |
| US-3987182-A | NOVEL BENZIMIDAZOLES USEFUL AS ANTI-ANDROGENS | SCHERING CORPORATION (US) | 1976-10-19 | — | — | US | disclosed |