Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11869359 | 0.73 | MAOB (0.68) | MAOBKDM4ESMN1; SMN2MAPTPOLB | |
| SCHEMBL11865039 | 0.73 | PTPN1 (0.54) | MAOBLMNAKMT2AMEN1HPGD | |
| SCHEMBL11393281 | 0.72 | LMNA (0.41) | LMNAKMT2AMEN1HPGDKDM4E | |
| SCHEMBL20588726 | 0.72 | LMNA (0.64) | LMNAKMT2AMEN1HPGDKDM4E | |
| SCHEMBL11862946 | 0.72 | NQO1 (0.46) | MAOBHPGDKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11398826 | 0.72 | LMNA (0.47) | MAOBLMNAKMT2AMEN1HPGD | |
| SCHEMBL21591575 | 0.71 | MAOB (0.65) | MAOBLMNAKMT2AMEN1HPGD | |
| SCHEMBL11617058 | 0.71 | MAOB (0.65) | MAOBLMNAHPGDKDM4ESMN1; SMN2 | |
| SCHEMBL21591578 | 0.70 | MAOB (0.63) | MAOBLMNAKMT2AHPGDKDM4E | |
| SCHEMBL11624553 | 0.70 | MAOB (0.63) | MAOBKMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959480-A | Polycyclic gamma-pyrone-3-carboxaldehyde derivatives | WARNER-LAMBERT COMPANY (US) | 1976-05-25 | — | — | US | disclosed |