Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | CA12 | O43570 | 2/20 | 0.73 |
| ▸ | CA1 | P00915 | 2/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.73 |
| ▸ | CA6 | P23280 | 2/20 | 0.73 |
| ▸ | CA5A | P35218 | 2/20 | 0.73 |
| ▸ | CA7 | P43166 | 2/20 | 0.73 |
| ▸ | CA9 | Q16790 | 2/20 | 0.73 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.73 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | CA4 | P22748 | 1/20 | 0.73 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.73 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.73 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.73 |
| ▸ | APP | P05067 | 9/20 | 0.59 |
| ▸ | TEX264 | Q9Y6I9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677159 | 0.88 | ALDH1A1 (0.55) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL30331814 | 0.88 | CISD1 (0.81) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL12418660 | 0.88 | CISD1 (0.81) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11790865 | 0.86 | CISD1 (0.74) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL11202416 | 0.85 | ALDH1A1 (0.67) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL2615437 | 0.84 | CISD1 (0.76) | CISD1ALDH1A1CA12CA1CA2 | |
| Furosemide SCHEMBL29406913 | 0.84 | CISD1 (1.00) | CISD1ALDH1A1CA12CA1CA2 | |
| SCHEMBL13107613 | 0.84 | CISD1 (0.76) | CISD1ALDH1A1CA12CA1CA2 | |
| Furosemide SCHEMBL428921 | 0.84 | CISD1 (1.00) | CISD1ALDH1A1CA12CA1CA2 | |
| Furosemide SCHEMBL9811 | 0.84 | CISD1 (1.00) | CISD1ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959261-A | DIURETICS, SALURETICS | BOEHRINGER MANNHEIM GMBH (DT) | 1976-05-25 | — | — | US | claimed |
| US-3959261-A | DIURETICS, SALURETICS | BOEHRINGER MANNHEIM GMBH (DT) | 1976-05-25 | — | — | US | disclosed |