Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11871919 | 0.88 | LMNA (0.60) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL11582546 | 0.88 | LMNA (0.63) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL11583159 | 0.86 | LMNA (0.59) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL11584563 | 0.82 | LMNA (0.63) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL11881204 | 0.81 | LMNA (0.61) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL11873463 | 0.80 | CASP1 (0.46) | LMNACASP1KDM4ETSHRALDH1A1 | |
| SCHEMBL3526298 | 0.80 | TSHR (0.54) | LMNAKDM4EMAPK1TSHRTDP1 | |
| SCHEMBL11874422 | 0.79 | LMNA (0.57) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL11582889 | 0.79 | LMNA (0.77) | LMNACASP1NPSR1KDM4EMAPK1 | |
| SCHEMBL3530225 | 0.79 | TSHR (0.51) | LMNANPSR1KDM4EMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962443-A | Antibacterial pharmaceutical compositions and processes for preparation thereof | DAINIPPON PHARMACEUTICAL CO., LTD. (JA) | 1976-06-08 | — | — | US | disclosed |