Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864169 | 0.87 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11874915 | 0.87 | CUL4A (0.36) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11874188 | 0.79 | MAPT (0.32) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11867415 | 0.75 | NOTUM (0.37) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11875487 | 0.75 | ADORA3 (0.56) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11868175 | 0.75 | GAA (0.45) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11868525 | 0.75 | CHEK1 (0.58) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11868935 | 0.75 | ADORA3 (0.56) | MAPTALDH1A1KDM4EMAPK1HTT | |
| SCHEMBL11872864 | 0.74 | KDM4E (0.32) | MAPTALDH1A1KDM4EHTTCUL4A | |
| SCHEMBL11869822 | 0.73 | SMN1; SMN2 (0.35) | MAPTALDH1A1KDM4EMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987196-A | FUNGISTATS | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |