Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11868175 | 0.87 | GAA (0.45) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL4586177 | 0.81 | NPM1 (0.37) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL11868935 | 0.81 | ADORA3 (0.56) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL11864169 | 0.80 | ALDH1A1 (0.40) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL11871280 | 0.78 | ADORA3 (0.36) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL5050800 | 0.77 | KCNJ1 (0.37) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL4585307 | 0.77 | ADORA3 (0.35) | ADORA3ADORA1ADORA2AMAPTKDM4E | |
| SCHEMBL11868424 | 0.77 | PKM (0.41) | ADORA3ADORA1ADORA2APOLB | |
| SCHEMBL1602588 | 0.76 | ADORA3 (0.54) | ADORA3MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL11874157 | 0.75 | MAPT (0.38) | ADORA3ADORA1ADORA2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987196-A | FUNGISTATS | ELI LILLY AND COMPANY (US) | 1976-10-19 | — | — | US | disclosed |