Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.61 |
| ▸ | IRAK4 | Q9NWZ3 | 10/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6390772 | 0.86 | MEN1 (0.51) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| Fenbendazole SCHEMBL31547342 | 0.85 | LMNA (0.82) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| Fenbendazole SCHEMBL31547327 | 0.85 | LMNA (0.82) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| Fenbendazole SCHEMBL166352 | 0.85 | LMNA (0.82) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| Fenbendazole SCHEMBL3988034 | 0.85 | LMNA (0.82) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| SCHEMBL31154057 | 0.85 | MEN1 (0.54) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| Fenbendazole SCHEMBL28228589 | 0.84 | LMNA (0.80) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| Fenbendazole SCHEMBL9639071 | 0.84 | LMNA (0.80) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| SCHEMBL11872088 | 0.83 | LMNA (0.65) | MEN1KMT2ALMNACYP1A2NR1I2 | |
| SCHEMBL11881074 | 0.83 | LMNA (0.65) | MEN1KMT2ALMNACYP1A2NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3965113-A | 5(6)-Benzene ring substituted benzimidazole-2-carbamate derivatives having anthelmintic activity | SYNTEX (U.S.A.) INC. (US) | 1976-06-22 | — | — | US | disclosed |