Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11874467 | 1.00 | MAPT (0.45) | MAPTPOLBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL30037334 | 0.82 | SLC7A5 (0.61) | MAPTPOLBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL3059437 | 0.82 | SLC7A5 (0.61) | MAPTPOLBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL4943107 | 0.82 | SLC7A5 (0.61) | MAPTPOLBSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL919742 | 0.80 | KIF11 (0.56) | GAAKIF11ALDH1A1 | |
| SCHEMBL5696373 | 0.80 | KIF11 (0.57) | KIF11ALDH1A1GLO1 | |
| SCHEMBL1158094 | 0.80 | KIF11 (0.56) | GAAKIF11ALDH1A1 | |
| SCHEMBL11796402 | 0.80 | KIF11 (0.57) | KIF11ALDH1A1GLO1 | |
| SCHEMBL1158095 | 0.80 | KIF11 (0.56) | GAAKIF11ALDH1A1 | |
| SCHEMBL31065560 | 0.79 | GAA (0.60) | MAPTPOLBTSHRGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976781-A | SULFUR CONTAINING AMINES | L'OREAL (FR) | 1976-08-24 | — | — | US | claimed |