Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | PPARA | Q07869 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611110 | 0.86 | CTSK (0.49) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL23611112 | 0.86 | CTSK (0.49) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL11877264 | 0.85 | CTSK (0.50) | CTSKCTSSMAPTPPARGPPARA | |
| SCHEMBL11876457 | 0.84 | CTSS (0.47) | CTSKCTSSPPARGHDAC4HDAC1 | |
| SCHEMBL8867310 | 0.83 | CTSS (0.46) | CTSKCTSSGABRB1GABRB2ATM | |
| SCHEMBL11573224 | 0.83 | CTSK (0.46) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL8867317 | 0.83 | CTSS (0.46) | CTSKCTSSGABRB1GABRB2ATM | |
| SCHEMBL11880230 | 0.81 | L3MBTL1 (0.48) | CTSKCTSSGABRB1GABRB2PPARG | |
| SCHEMBL11573817 | 0.81 | CTSS (0.47) | CTSKCTSSGABRB1GABRB2MAPT | |
| SCHEMBL10891091 | 0.81 | CTSK (0.51) | CTSKCTSSGABRB1GABRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3988451-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3931160-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |