Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11877622 | 0.83 | CLCN2 (0.39) | TSHRMEN1TP53CYP3A4MAPT | |
| SCHEMBL3630534 | 0.79 | CTRC (0.44) | TYRTHRBTHRA | |
| SCHEMBL11883381 | 0.78 | THRB (0.60) | TSHRMEN1TP53CYP3A4MAPT | |
| SCHEMBL10709892 | 0.71 | TYR (0.46) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL9651734 | 0.70 | TYR (0.44) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL19987931 | 0.70 | CNR2 (0.40) | CYP3A4MAPTTDP1PPARAPPARG | |
| SCHEMBL9717548 | 0.70 | TYR (0.56) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL28519385 | 0.70 | PPARA (0.38) | TYRTSHRMEN1TP53CYP3A4 | |
| SCHEMBL7645227 | 0.69 | BID (0.57) | TSHRMAPTALOX15BIDMCL1 | |
| Ammonia Solution, Strong SCHEMBL27533196 | 0.69 | TYR (0.47) | TYRTSHRMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3950539-A | Substituted diaminoguanidines | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | disclosed |