SCHEMBL19987931

SCHEMBL19987931

CCCc1ccc(C(=O)c2ccc(CCC)c(Cl)c2Cl)c(Cl)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 8/20 0.40
PRKCI P41743 1/20 0.40
FLT1 P17948 1/20 0.39
FLT4 P35916 1/20 0.39
KDR P35968 1/20 0.39
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
CLCN2 P51788 1/20 0.35
CNR1 P21554 2/20 0.35
POLB P06746 2/20 0.34
KDM4E B2RXH2 2/20 0.34
ALDH1A1 P00352 2/20 0.34
GAA P10253 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
CA12 O43570 1/20 0.34
MAPT P10636 2/20 0.34
NPC1 O15118 1/20 0.34
CASP3 P42574 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14244545 0.83 PPARG (0.38) CNR2FLT1FLT4KDRCYP1A2
SCHEMBL3630534 0.77 CTRC (0.44) CNR2PRKCIKDM4EALDH1A1THRB
SCHEMBL9114093 0.74 PRKCI (0.47) CNR2PRKCICYP3A4CNR1MAPT
SCHEMBL10061111 0.73 TAAR1 (0.39) PRKCICYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL27308477 0.72 CLCN2 (0.54) CYP1A2CYP3A4CYP2D6CYP2C19CLCN2
SCHEMBL9710256 0.71 CLCN2 (0.42) FLT1FLT4KDRCYP1A2CYP3A4
Hydrochloric Acid SCHEMBL28243602 0.71 CLCN2 (0.53) CYP1A2CYP3A4CYP2D6CYP2C19CLCN2
SCHEMBL8467585 0.71 CLCN2 (0.42) CLCN2KDM4EALDH1A1GAAL3MBTL1
SCHEMBL7644126 0.70 TSHR (0.53) CLCN2ALDH1A1CA12PPARGPPARA
SCHEMBL11875855 0.70 TYR (0.39) CYP3A4MAPTTHRBTDP1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE (US) 2026-02-24 US disclosed
EP-3299514-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE EUROPE GMBH (DE) 2024-11-06 EP disclosed
CN-110835506-B Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2022-11-04 CN disclosed
CN-107869054-B Adhesive-reinforced textile, method for the production thereof and use thereof 约翰斯曼维尔欧洲有限公司 2022-05-03 CN disclosed
EP-3779015-B1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE JOHNS MANVILLE (US) 2021-12-08 EP disclosed
US-10934460-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2021-03-02 US disclosed
EP-3779015-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville (US) 2021-02-17 EP disclosed
CN-110835506-A Adhesive-reinforced textile fabric, method for the production thereof and use thereof 约翰斯曼维尔公司 2020-02-25 CN disclosed
US-20200056327-A1 Binder-consolidated textile fabric, method for its manufacture and its use JOHNS MANVILLE 2020-02-20 US disclosed
US-10472546-B2 Binder-consolidated textile fabrics and methods of their manufacture and use JOHNS MANVILLE (US) 2019-11-12 US disclosed
US-20180086951-A1 BINDER-CONSOLIDATED TEXTILE FABRICS AND METHODS OF THEIR MANUFACTURE AND USE JOHNS MANVILLE 2018-03-29 US disclosed
EP-3299514-A1 BINDER-CONSOLIDATED TEXTILE FABRIC, METHOD FOR ITS MANUFACTURE AND ITS USE Johns Manville Europe GmbH (DE) 2018-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559884-B2 Binder-consolidated textile fabric, method for its manufacture and its use SEM1, SMCHD1, SMC4 CNR2 2697/4885PRKCI 4446/4885FLT1 3433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.