Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881073 | 0.89 | ALOX5 (0.50) | BCHEACHEALOX5CYP1A2LTA4H | |
| SCHEMBL11875284 | 0.88 | TSHR (0.60) | MAOBBCHEACHETSHR | |
| SCHEMBL11877098 | 0.83 | ESR1 (0.55) | BCHEACHECYP1A2LTA4HCYP2D6 | |
| SCHEMBL11874704 | 0.81 | NR4A2 (0.59) | MAOBHDAC6ALOX5PTGESCYP1A2 | |
| SCHEMBL1122672 | 0.81 | PKM (0.63) | MAOBBCHEACHEHDAC4HDAC1 | |
| SCHEMBL11883196 | 0.80 | CYP19A1 (0.52) | CYP1A2LTA4H | |
| SCHEMBL11877323 | 0.79 | LTA4H (0.51) | MAOBBCHEACHEHDAC4HDAC1 | |
| SCHEMBL11880836 | 0.79 | EBP (0.53) | BCHEACHECYP1A2LTA4HCYP2D6 | |
| SCHEMBL11873791 | 0.79 | LSS (0.56) | BCHEACHEHDAC6 | |
| SCHEMBL11873224 | 0.79 | BCHE (0.59) | BCHEACHECYP1A2LTA4HCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960886-A | Substituted N-arylanilines | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | disclosed |