Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14784780 | 0.79 | LMNA (0.35) | LMNACETPALDH1A1HSD17B10 | |
| SCHEMBL6029543 | 0.79 | LMNA (0.44) | LMNA | |
| SCHEMBL2262667 | 0.76 | CETP (0.39) | CETPALDH1A1HSD17B10 | |
| SCHEMBL1023713 | 0.76 | LMNA (0.58) | LMNA | |
| SCHEMBL199 | 0.76 | CETP (0.39) | CETPALDH1A1HSD17B10 | |
| SCHEMBL2852867 | 0.76 | CETP (0.39) | CETPALDH1A1HSD17B10 | |
| Chloroform SCHEMBL5313122 | 0.74 | ALDH1A1 (0.41) | LMNACETPALDH1A1HSD17B10 | |
| Chloroform SCHEMBL6152248 | 0.74 | ALDH1A1 (0.41) | LMNACETPALDH1A1HSD17B10 | |
| SCHEMBL11204825 | 0.73 | LMNA (0.32) | LMNA | |
| Water SCHEMBL17223739 | 0.72 | CETP (0.37) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190119462-A1 | Porous Polymer Scaffolds, and Methods of Making and Using the Same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-04-25 | — | — | US | claimed |
| EP-3468704-A1 | POROUS POLYMER SCAFFOLDS, AND METHODS OF MAKING AND USING THE SAME | The Regents of The University of California (US) | 2019-04-17 | — | — | EP | claimed |
| WO-2017218565-A1 | POROUS POLYMER SCAFFOLDS, AND METHODS OF MAKING AND USING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-12-21 | — | — | WO | claimed |
| US-8471006-B2 | Coupling agents for peptide synthesis | UNIVERSITY OF MASSACHUSETTS (US) | 2013-06-25 | — | — | US | disclosed |
| US-20120277428-A1 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2012-11-01 | — | — | US | disclosed |
| US-8217169-B2 | Coupling agents for peptide synthesis | UNIVERSITY OF MASSACHUSETTS (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110028720-A1 | New Coupling Agents for Peptide Synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-02-03 | — | — | US | disclosed |
| US-7812158-B2 | Coupling agents for peptide synthesis | UNIVERSITY OF MASSACHUSETTS (US) | 2010-10-12 | — | — | US | disclosed |
| EP-1687318-A4 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | UNIV MASSACHUSETTS (US) | 2009-01-07 | — | — | EP | disclosed |
| US-20070112196-A1 | New coupling agents for peptide synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-05-17 | — | — | US | disclosed |
| CN-1898254-A | New coupling agents for peptide synthesis | UNIV MASSACHUSETTS (US) | 2007-01-17 | — | — | CN | disclosed |
| EP-1687318-A2 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | University of Massachusetts (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005042562-A2 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | THE UNIVERSITY OF MASSACHUSETTS (US) | 2005-05-12 | — | — | WO | disclosed |
| JP-2002371028-A | METHOD FOR PRODUCING 3,3,3-TRIFLUORO-2-HYDROXYPROPIONIC ACID DERIVATIVE | CENTRAL GLASS CO LTD | 2002-12-26 | — | — | JP | disclosed |
| US-3994871-A | Process for the manufacture of peptides containing cystine | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120277428-A1 | NEW COUPLING AGENTS FOR PEPTIDE SYNTHESIS | NGLY1, NPPA, VIP | LMNA 4717/4885CETP 2404/4885ALDH1A1 4753/4885 |
| US-20070112196-A1 | New coupling agents for peptide synthesis | NGLY1, NPPA, VIP | LMNA 4649/4885CETP 2754/4885ALDH1A1 4756/4885 |
| US-20110028720-A1 | New Coupling Agents for Peptide Synthesis | NGLY1, NPPA, VIP | LMNA 4717/4885CETP 2404/4885ALDH1A1 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.