Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2940920 | 0.88 | KDM4E (0.50) | MAPK1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL1808815 | 0.81 | CYP3A4 (0.55) | MAPK1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL12203984 | 0.80 | KDM4E (0.53) | CYP3A4ALDH1A1NPC1RAB9AKDM4E | |
| SCHEMBL24894090 | 0.80 | CYP3A4 (0.44) | MAPK1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL6362994 | 0.78 | LMNA (0.42) | MAPK1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL1939218 | 0.78 | ALDH1A1 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL11752648 | 0.78 | MCL1 (0.37) | CYP3A4MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL1025612 | 0.77 | ALDH1A1 (0.64) | MAPK1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL8809913 | 0.77 | CA12 (0.57) | MAPK1CYP3A4TSHRMEN1KMT2A | |
| SCHEMBL12110770 | 0.77 | MAPK1 (0.50) | MAPK1CYP3A4TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957860-A | SULFAMIC ACID | CIBA-GEIGY AG (CH) | 1976-05-18 | — | — | US | disclosed |