SCHEMBL8809913

SCHEMBL8809913

CCCSc1ccc(N)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA2 P00918 1/20 0.57
CA7 P43166 1/20 0.57
CA13 Q8N1Q1 1/20 0.57
MAOA P21397 2/20 0.55
MAOB P27338 2/20 0.55
MAPK1 P28482 3/20 0.46
TSHR P16473 3/20 0.46
CYP3A4 P08684 2/20 0.46
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.44
ALDH1A1 P00352 4/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
AR P10275 2/20 0.40
SLC2A1 P11166 1/20 0.38
TDP1 Q9NUW8 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13397872 0.87 CA12 (0.61) CA12CA1CA2CA7CA13
SCHEMBL422539 0.86 MAOA (0.58) CA12CA1CA2CA7CA13
SCHEMBL1808815 0.85 CYP3A4 (0.55) CA12CA1CA2CA7CA13
SCHEMBL11245186 0.85 MAOA (0.51) CA12CA1CA2CA7CA13
SCHEMBL8878775 0.83 MAOA (0.50) CA12CA1CA2CA7CA13
SCHEMBL11041011 0.83 MAOA (0.50) CA12CA1CA2CA7CA13
SCHEMBL12110770 0.80 MAPK1 (0.50) CA2MAOAMAOBMAPK1TSHR
SCHEMBL13397873 0.80 CA12 (0.55) CA12CA1CA2CA7CA13
SCHEMBL4523181 0.80 SLC6A4 (0.52) MAOAMAPK1TSHRCYP3A4KMT2A
SCHEMBL10528392 0.80 SLC2A1 (0.55) CA12CA1CA2CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122028594-A Solar cell, preparation method thereof, photovoltaic module, power utilization device and power generation device 宁德时代新能源科技股份有限公司 2026-05-12 CN claimed
CN-101270068-B Method for preparing 2-nitryl-4-propylthioaniline CHANGZHOU YABANG QIHUI PHARMACEUTICAL CHEMICAL ENGINEERING CO LTD 2011-05-18 CN claimed
CN-122028594-A Solar cell, preparation method thereof, photovoltaic module, power utilization device and power generation device 宁德时代新能源科技股份有限公司 2026-05-12 CN disclosed
CN-111448510-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2023-03-14 CN disclosed
CN-111433665-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2023-02-28 CN disclosed
US-20210283139-A1 BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 AMPHISTA THERAPEUTICS LIMITED (GB) 2021-09-16 US disclosed
CN-108892643-B Novel preparation method of albendazole 常州齐晖药业有限公司 2021-01-08 CN disclosed
CN-111448510-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2020-07-24 CN disclosed
CN-111433665-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2020-07-17 CN disclosed
EP-3653660-A1 THERMALLY CONDUCTIVE MATERIAL, DEVICE PROVIDED WITH THERMALLY CONDUCTIVE LAYER, THERMALLY CONDUCTIVE MATERIAL FORMATION COMPOSITION, DISC-SHAPED LIQUID CRYSTAL COMPOUND FUJIFILM Corporation (JP) 2020-05-20 EP disclosed
CN-105733610-B Composition containing polyamic acid polymer, liquid crystal aligning agent, liquid crystal aligning film and liquid crystal display element JSR株式会社 2019-12-17 CN disclosed
CN-101270068-B Method for preparing 2-nitryl-4-propylthioaniline CHANGZHOU YABANG QIHUI PHARMACEUTICAL CHEMICAL ENGINEERING CO LTD 2011-05-18 CN disclosed
CN-101270091-B Method for preparing albendazole CHANGZHOU YABANG QIHUI PHARMACEUTICAL CHEMICAL ENGINEERING CO LTD 2010-12-29 CN disclosed
CN-101270068-A Method for preparing 2-nitryl-4-propylthioaniline CHANGZHOU YABANG QIHUI PHARMAC (CN) 2008-09-24 CN disclosed
CN-101270091-A Method for preparing albendazole CHANGZHOU YABANG QIHUI PHARMAC (CN) 2008-09-24 CN disclosed
WO-1997013748-A1 SULFOXIDE DERIVATIVES OF NITROGEN-MUSTARD AND ANTICANCER AGENT CONTAINING THE SAME CHONG KUN DANG CORP. (KR) 1997-04-17 WO disclosed
US-4791129-A RHEUMATIC DISEASES; ANTIARTHRITIC AGENTS PFIZER INC. (US) 1988-12-13 US disclosed
US-4725616-A ANTIARTHRITIC AGENTS PFIZER INC. (US) 1988-02-16 US disclosed
EP-0208510-A2 1-Substituted oxindole-3-carboxamines as antiinflammatory and analgesic agents PFIZER INC. (US) 1987-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210283139-A1 BIFUNCTIONAL MOLECULES FOR TARGETING UCHL5 UCHL5, UCHL3, UCHL1 CA12 4247/4885CA1 4039/4885CA2 4667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.