Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GLA | P06280 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 3/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187275 | 0.86 | ALDH1A1 (0.58) | ALDH1A1KMT2AGLAHPGDRAB9A | |
| SCHEMBL27961756 | 0.84 | ALDH1A1 (0.56) | ALDH1A1KMT2AGLAHPGDRAB9A | |
| SCHEMBL28560797 | 0.84 | ALDH1A1 (0.46) | ALDH1A1KMT2AGLAHPGDRAB9A | |
| SCHEMBL4014126 | 0.84 | KMT2A (0.64) | ALDH1A1KMT2AGLAHPGDRAB9A | |
| SCHEMBL29410608 | 0.80 | DNMT1 (0.59) | ALDH1A1KMT2AHPGDRAB9AKDM4E | |
| SCHEMBL196007 | 0.80 | DNMT1 (0.59) | ALDH1A1KMT2AHPGDRAB9AKDM4E | |
| SCHEMBL29787010 | 0.80 | DNMT1 (0.59) | ALDH1A1KMT2AHPGDRAB9AKDM4E | |
| SCHEMBL31307687 | 0.79 | DNMT1 (0.57) | ALDH1A1KMT2AHPGDRAB9AKDM4E | |
| SCHEMBL29810649 | 0.79 | DNMT1 (0.57) | ALDH1A1KMT2AHPGDRAB9AKDM4E | |
| SCHEMBL1187919 | 0.78 | ALDH1A1 (0.56) | ALDH1A1KMT2AGLAHPGDRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7888509-B2 | Chiral 1,8-diarylnaphthalenes, methods of making them, and their use as sensors | GEORGETOWN UNIVERSITY (US) | 2011-02-15 | — | — | US | disclosed |
| US-20070276140-A1 | Chiral 1,8-Diarylnaphthalenes, Methods of Making Them, and Their Use as Sensors | GEORGETOWN UNIVERSITY (US) | 2007-11-29 | — | — | US | disclosed |
| WO-2005043124-A2 | CHIRAL 1,8-DIARYLNAPHTHALENES, METHODS OF MAKING THEM, AND THEIR USE AS SENSORS | GEORGETOWN UNIVERSITY (US) | 2005-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276140-A1 | Chiral 1,8-Diarylnaphthalenes, Methods of Making Them, and Their Use as Sensors | ALKBH2, ALKBH1, ALG3 | ALDH1A1 39/4885KMT2A 1186/4885GLA 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.