Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SCN1A | P35498 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6539479 | 0.80 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL9769982 | 0.79 | ALDH1A1 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL25922262 | 0.76 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL30349741 | 0.76 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL25921496 | 0.76 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL23435385 | 0.76 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL10713621 | 0.76 | KCNH2 (0.39) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL24901344 | 0.76 | KCNH2 (0.40) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL20863035 | 0.76 | KCNH2 (0.42) | KCNH2KCNA5LMNAKMT2AALDH1A1 | |
| SCHEMBL24590304 | 0.76 | KMT2A (0.44) | KCNH2KCNA5LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3969392-A | PARASITICIDE, BACTERICIDE, ANTIINFLAMMATORY, SURFACTANT | E. R. SQUIBB & SONS, INC. (US) | 1976-07-13 | — | — | US | disclosed |