Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252215 | 0.86 | RORC (0.46) | RORCHTTPOLBALDH1A1MAPT | |
| SCHEMBL11876436 | 0.82 | GRIN2D (0.63) | HTTPOLBALDH1A1GRIN2DGRIN3B | |
| SCHEMBL7122790 | 0.82 | SMN1; SMN2 (0.59) | RORCHTTALDH1A1MAPTPKM | |
| SCHEMBL30168169 | 0.82 | SMN1; SMN2 (0.59) | RORCHTTALDH1A1MAPTPKM | |
| Nitric Acid SCHEMBL3858360 | 0.79 | GRIN2D (0.60) | HTTPOLBALDH1A1GRIN2DGRIN3B | |
| SCHEMBL11880298 | 0.79 | MAPT (0.52) | RORCHTTALDH1A1GRIN2DGRIN3B | |
| SCHEMBL1583292 | 0.79 | HTT (0.59) | HTTPOLBALDH1A1MAPTKMT2A | |
| SCHEMBL30078131 | 0.79 | HTT (0.59) | HTTPOLBALDH1A1MAPTKMT2A | |
| SCHEMBL11878500 | 0.79 | GAA (0.56) | POLBALDH1A1MAPTRAB9APKM | |
| SCHEMBL4476089 | 0.79 | MAPT (0.56) | HTTALDH1A1MAPTRAB9APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976643-A | FROM AN ANILINE AND CYANAMIDE | WILLIAM H. RORER, INC. (US) | 1976-08-24 | — | — | US | disclosed |