Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1430242 | 0.73 | MAPT (0.50) | HPGDALDH1A1MAPTHTTRAB9A | |
| SCHEMBL21089025 | 0.73 | KMT2A (0.37) | L3MBTL1HPGDALDH1A1MAPTHTT | |
| SCHEMBL989524 | 0.72 | — | — | |
| SCHEMBL8823669 | 0.71 | HPGD (0.46) | L3MBTL1HPGDALDH1A1MAPTHTT | |
| SCHEMBL14106778 | 0.71 | CA1 (0.55) | L3MBTL1HPGDALDH1A1MAPTHTT | |
| SCHEMBL2356967 | 0.71 | MAPT (0.48) | L3MBTL1HPGDALDH1A1MAPTHTT | |
| SCHEMBL10625640 | 0.71 | MAPT (0.46) | L3MBTL1HPGDALDH1A1MAPTHTT | |
| SCHEMBL1189820 | 0.71 | PDE4D (0.44) | HPGDALDH1A1MAPTRAB9AMEN1 | |
| SCHEMBL1005759 | 0.71 | SMN1; SMN2 (0.53) | L3MBTL1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL21089400 | 0.71 | ANPEP (0.41) | L3MBTL1HPGDALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2629345-B1 | ORGANIC ELECTROLUMINESCENT ELEMENT | NIPPON STEEL & SUMIKIN CHEM CO (JP) | 2017-12-06 | — | — | EP | disclosed |
| EP-2489659-A1 | Modulators of ATP-binding cassette transporters | Vertex Pharmaceuticals Incorporated (US) | 2012-08-22 | — | — | EP | disclosed |
| US-20110155660-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC | 2011-06-30 | — | — | US | disclosed |
| US-7882963-B2 | modifying polyamide discriminating layer ( e.g metaphenylene diamine- trimesoyl chloride monomers) with aminoacetophenone or aminothiophenol; fouling resistant surface, improved salt rejection, antimicrobial properties, improved solute, and/or small organics rejection; for water purification | DOW GLOBAL TECHNOLOGIES INC. (US) | 2011-02-08 | — | — | US | disclosed |
| US-20090159527-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES LLC | 2009-06-25 | — | — | US | disclosed |
| WO-2007133362-A1 | MODIFIED MEMBRANE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-11-22 | — | — | WO | disclosed |