Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28378687 | 0.79 | MAPT (0.45) | ANPEPHPGDALDH1A1MAPTGAA | |
| SCHEMBL21089025 | 0.76 | KMT2A (0.37) | L3MBTL1HPGDALDH1A1MAPTKMT2A | |
| SCHEMBL2255462 | 0.72 | ALDH1A1 (0.50) | L3MBTL1ATMHPGDALDH1A1MAPT | |
| SCHEMBL1188008 | 0.71 | L3MBTL1 (0.42) | L3MBTL1HPGDALDH1A1MAPTKMT2A | |
| SCHEMBL28607126 | 0.71 | IDO1 (0.49) | ANPEPL3MBTL1ATMALDH1A1MAPT | |
| SCHEMBL20960317 | 0.70 | ALDH1A1 (0.46) | HPGDALDH1A1KMT2AGAASMN1; SMN2 | |
| SCHEMBL15325740 | 0.68 | ANPEP (0.49) | ANPEPL3MBTL1ATMALDH1A1MAPT | |
| SCHEMBL9908238 | 0.67 | TDP1 (0.46) | ANPEPL3MBTL1ATMHPGDALDH1A1 | |
| SCHEMBL6468101 | 0.67 | KMT2A (0.59) | L3MBTL1ATMHPGDALDH1A1MAPT | |
| SCHEMBL29671577 | 0.67 | KMT2A (0.59) | L3MBTL1ATMHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |