Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23181 | 0.82 | MAPK1 (0.55) | MAPTMAPK1ALDH1A1KDM4EPOLB | |
| Hydrogen Sulfide SCHEMBL20395887 | 0.80 | MAPK1 (0.53) | MAPTMAPK1ALDH1A1KDM4EPOLB | |
| SCHEMBL11318668 | 0.79 | CYP1A2 (0.44) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL14312097 | 0.78 | GAA (0.53) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL11803039 | 0.77 | MAPK1 (0.47) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL14883115 | 0.77 | MAPT (0.47) | MAPTMAPK1LMNAL3MBTL1GAA | |
| SCHEMBL14700343 | 0.77 | MAPT (0.47) | MAPTMAPK1MEN1KMT2AGAA | |
| SCHEMBL4115128 | 0.77 | MAPT (0.47) | MAPTMAPK1LMNAL3MBTL1GAA | |
| SCHEMBL4111687 | 0.77 | MAPK1 (0.47) | MAPTMAPK1MEN1KMT2ALMNA | |
| SCHEMBL10798317 | 0.76 | MAPK1 (0.50) | MAPTMAPK1POLBCDK1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936523-A | CROSSLINKED POLYETHYLENE | SIEMENS AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | claimed |
| US-3936523-A | CROSSLINKED POLYETHYLENE | SIEMENS AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |