Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14312244 | 0.96 | GAA (0.53) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10891276 | 0.83 | MAPT (0.62) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL14312203 | 0.83 | GAA (0.42) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL23181 | 0.81 | MAPK1 (0.55) | MAPTMAPK1TSHRPOLBALDH1A1 | |
| SCHEMBL14312207 | 0.81 | GAA (0.43) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| Hydrogen Sulfide SCHEMBL20395887 | 0.79 | MAPK1 (0.53) | MAPTMAPK1TSHRPOLBALDH1A1 | |
| SCHEMBL11881122 | 0.78 | MAPT (0.43) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL10921913 | 0.78 | GAA (0.80) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL8073238 | 0.78 | SLC29A1 (0.43) | GAAMAPTMAPK1SMN1; SMN2NPC1 | |
| SCHEMBL14312267 | 0.78 | GAA (0.50) | GAAMAPTMAPK1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8987383-B2 | Triazine derivatives and application thereof | NIPPON KASEI CHEMICAL COMPANY LIMITED (JP) | 2015-03-24 | — | — | US | disclosed |
| US-20130023629-A1 | TRIAZINE DERIVATIVES AND APPLICATION THEREOF | SHINRYO CORPORATION (JP) | 2013-01-24 | — | — | US | disclosed |
| EP-2537833-A1 | TRIAZINE DERIVATIVE, AND APPLICATION THEREOF | Nippon Kasei Chemical Company Limited (JP) | 2012-12-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023629-A1 | TRIAZINE DERIVATIVES AND APPLICATION THEREOF | HSPH1, PRDX3, PRXL2A | GAA 2987/4885MAPT 2771/4885MAPK1 4162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.