Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11376657 | 0.76 | LMNA (0.43) | LMNA | |
| SCHEMBL6806663 | 0.71 | LMNA (0.42) | LMNA | |
| SCHEMBL11883266 | 0.70 | LMNA (0.39) | LMNA | |
| SCHEMBL28227259 | 0.68 | LMNA (0.47) | LMNA | |
| SCHEMBL10673456 | 0.62 | MEN1 (0.38) | LMNA | |
| SCHEMBL11456463 | 0.61 | LMNA (0.37) | LMNA | |
| SCHEMBL366863 | 0.61 | MMP3 (0.56) | LMNA | |
| SCHEMBL10994127 | 0.60 | LMNA (0.36) | LMNA | |
| SCHEMBL11213304 | 0.60 | MEN1 (0.38) | LMNA | |
| SCHEMBL11199210 | 0.60 | CES2 (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3728345-A | PREPARATION OF QUINOXALINE-2-CARBOXAMIDE DERIVATIVES | PFIZER | 1973-04-17 | — | — | US | disclosed |