Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CNOT7 | Q9UIV1 | 2/20 | 0.60 |
| ▸ | PARN | O95453 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012556 | 0.93 | ALDH1A1 (0.77) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL17786242 | 0.85 | ALDH1A1 (1.00) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL18166667 | 0.83 | ALDH1A1 (0.61) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL683583 | 0.81 | ADORA2B (0.72) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL14754322 | 0.81 | ALDH1A1 (0.69) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL10501627 | 0.79 | TSHR (0.74) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL1944405 | 0.79 | ADORA2B (1.00) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL16120979 | 0.78 | ADORA2B (0.85) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL16120975 | 0.78 | ADORA2B (0.88) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 | |
| SCHEMBL10895834 | 0.78 | TSHR (0.72) | TSHRALDH1A1ADORA2BRXFP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3926995-A | ANTIALLERGY, BRONCHIODILATOR | KNOLL AG | 1975-12-16 | — | — | US | disclosed |