SCHEMBL118847

SCHEMBL118847

O=C(O)Nc1ccc(N2CCOCC2=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.60
PTGS2 P35354 5/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19647445 0.87 F10 (0.62) F10PTGS2
SCHEMBL1677899 0.87 F10 (0.60) F10PTGS2
SCHEMBL28407706 0.87 F10 (0.59) F10PTGS2
SCHEMBL19647435 0.87 F10 (0.59) F10PTGS2
SCHEMBL118728 0.85 F10 (0.58) F10PTGS2
SCHEMBL1679321 0.83 F10 (0.65) F10PTGS2
SCHEMBL6453826 0.82 F10 (0.64) F10PTGS2
SCHEMBL25207144 0.82 GAA (0.56) F10PTGS2
SCHEMBL2639314 0.82 F10 (0.62) F10PTGS2
SCHEMBL1380646 0.81 F10 (0.62) F10PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014170908-A1 PROCESS FOR PREPARATION OF OXAZOLIDINONE DERIVATIVES NOSCH LABS PRIVATE LIMITED (IN) 2014-10-23 WO disclosed
US-20140128601-A1 PROCESS FOR OBTAINING RIVAROXABAN AND INTERMEDIATE THEREOF INTERQUIM, S.A. (ES) 2014-05-08 US disclosed
EP-2710001-A1 PROCESS FOR OBTAINING RIVAROXABAN AND INTERMEDIATE THEREOF Interquim, S.A. (ES) 2014-03-26 EP disclosed
WO-2013120465-A1 A PROCESS FOR THE PREPARATION OF RIVAROXABAN BASED ON THE USE OF (S)-EPICHLOROHYDRIN ZENTIVA, K.S. (CZ) 2013-08-22 WO disclosed
WO-2012159992-A1 PROCESS FOR OBTAINING RIVAROXABAN AND INTERMEDIATE THEREOF INTERQUIM, S.A. (ES) 2012-11-29 WO disclosed
EP-2424847-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF Apotex Pharmachem Inc. (CA) 2012-03-07 EP disclosed
WO-2010124385-A1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC. (CA) 2010-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140128601-A1 PROCESS FOR OBTAINING RIVAROXABAN AND INTERMEDIATE THEREOF TFPI, CYP2C9, CYP2C19 F10 20/4885PTGS2 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.