SCHEMBL19647435

SCHEMBL19647435

O=C(S)Nc1ccc(N2CCOCC2=O)cc1

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 15/20 0.59
PTGS2 P35354 5/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118847 0.87 F10 (0.60) F10PTGS2
SCHEMBL19647445 0.86 F10 (0.62) F10PTGS2
SCHEMBL28407706 0.86 F10 (0.59) F10PTGS2
SCHEMBL1677899 0.86 F10 (0.60) F10PTGS2
SCHEMBL118728 0.83 F10 (0.58) F10PTGS2
SCHEMBL1679321 0.82 F10 (0.65) F10PTGS2
SCHEMBL6453826 0.81 F10 (0.64) F10PTGS2
SCHEMBL1380646 0.80 F10 (0.62) F10PTGS2
SCHEMBL5624965 0.79 F10 (0.59) F10PTGS2
SCHEMBL5625331 0.79 F10 (0.59) F10PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2630143-B1 PROCESSES FOR THE PREPARATION OF RIVAROXABAN AND INTERMEDIATES THEREOF APOTEX PHARMACHEM INC (CA) 2017-11-29 EP disclosed