Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6179994 | 0.92 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL6453826 | 0.86 | F10 (0.64) | F10PTGS2 | |
| SCHEMBL6181035 | 0.85 | F10 (0.60) | F10MAPT | |
| SCHEMBL1679321 | 0.85 | F10 (0.65) | F10PTGS2 | |
| SCHEMBL1381644 | 0.84 | F10 (0.60) | F10PTGS2 | |
| SCHEMBL1381539 | 0.84 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL6182831 | 0.84 | F10 (0.59) | F10MAPTPTGS2 | |
| SCHEMBL1380603 | 0.84 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL8324993 | 0.84 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL1379341 | 0.83 | F10 (0.55) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732757-B2 | — | — | 2011-07-27 | — | — | JP | claimed |
| JP-2006512321-A | — | — | 2006-04-13 | — | — | JP | claimed |
| EP-1571154-A1 | Beta-aminoacid-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-09-07 | — | — | EP | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | claimed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | claimed |
| EP-1571154-A1 | Beta-aminoacid-derivatives as factor Xa inhibitors | Aventis Pharma Deutschland GmbH (DE) | 2005-09-07 | — | — | EP | disclosed |