Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6181035 | 0.88 | F10 (0.60) | F10RAB9A | |
| SCHEMBL6453826 | 0.86 | F10 (0.64) | F10PTGS2 | |
| SCHEMBL1677899 | 0.85 | F10 (0.60) | F10POLBPTGS2 | |
| SCHEMBL1380646 | 0.85 | F10 (0.62) | F10PTGS2 | |
| SCHEMBL6182831 | 0.84 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL1380603 | 0.84 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL1381539 | 0.84 | F10 (0.59) | F10PTGS2 | |
| SCHEMBL118847 | 0.83 | F10 (0.60) | F10PTGS2 | |
| SCHEMBL118728 | 0.83 | F10 (0.58) | F10PTGS2 | |
| SCHEMBL28407706 | 0.82 | F10 (0.59) | F10PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4668614-B2 | — | — | 2011-04-13 | — | — | JP | claimed |
| JP-2006500369-A | — | — | 2006-01-05 | — | — | JP | claimed |
| EP-1558247-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GmbH (DE) | 2005-08-03 | — | — | EP | claimed |
| WO-2004017963-A1 | BENZIMIDAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-03-04 | — | — | WO | claimed |
| EP-1562939-A1 | CARBOXAMIDES | MERCK PATENT GmbH (DE) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046138-A1 | CARBOXAMIDES | MERCK PATENT GMBH (DE) | 2004-06-03 | — | — | WO | disclosed |