Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 7/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CDA | P32320 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11880313 | 0.81 | CRBN (0.35) | CRBN | |
| SCHEMBL7594726 | 0.81 | CRBN (0.35) | CRBN | |
| SCHEMBL20204642 | 0.77 | CRBN (0.47) | CRBNDDB1GAACDAMEN1 | |
| SCHEMBL7961031 | 0.74 | CRBN (0.52) | CRBNDDB1GAAMEN1ALDH1A1 | |
| SCHEMBL11568357 | 0.73 | CRBN (0.55) | CRBNDDB1GAACDAMEN1 | |
| SCHEMBL8531019 | 0.73 | ALDH1A1 (0.41) | MEN1ALDH1A1KMT2A | |
| SCHEMBL2193120 | 0.71 | CRBN (0.49) | CRBNDDB1GAACDAMEN1 | |
| SCHEMBL169034 | 0.69 | TSHR (0.48) | MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL26916219 | 0.69 | CRBN (0.47) | CRBNDDB1GAACDAMEN1 | |
| SCHEMBL18682176 | 0.68 | CRBN (0.46) | CRBNDDB1GAACDAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3867385-A | Binuclear n-heterocyclic polyglycidyl compounds, processes for their manufacture, and their use | CIBA GEIGY CORP | 1975-02-18 | — | — | US | disclosed |