SCHEMBL8531019

SCHEMBL8531019

O=C1NCCN1CC=CO

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
POLB P06746 3/20 0.41
KMT2A Q03164 3/20 0.38
MAPT P10636 2/20 0.38
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
MEN1 O00255 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
KDM4E B2RXH2 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
PER2 O15055 2/20 0.36
RAB9A P51151 1/20 0.35
RET P07949 1/20 0.34
KDR P35968 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1077228 0.80 ALDH1A1 (0.41) ALDH1A1POLBKMT2AMAPTCYP2C9
SCHEMBL166418 0.77
SCHEMBL3203792 0.77
SCHEMBL9283864 0.76 GPR4 (0.36)
SCHEMBL6285083 0.75
SCHEMBL11884792 0.73 CRBN (0.45) ALDH1A1KMT2AMEN1
SCHEMBL301524 0.72
SCHEMBL634568 0.72
SCHEMBL4037683 0.71 ALDH1A1 (0.50) ALDH1A1POLBKMT2AMAPTCYP2C9
SCHEMBL13236669 0.71 ALDH1A1 (0.50) ALDH1A1POLBKMT2AMAPTCYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112795175-A Manufacturing process of composite floor 浙江新远见材料科技股份有限公司 2021-05-14 CN claimed
CN-101088990-B Transesterification process for production of (meth)acrylate ester monomers ROHM & HAAS 2011-08-03 CN claimed
CN-101088990-A Transesterification process for production of (meth)acrylate ester monomers ROHM & HAAS (US) 2007-12-19 CN claimed
US-5288873-A Endcapped polyethers TEXACO CHEMICAL COMPANY (US) 1994-02-22 US claimed
JP-8311194-A None JP disclosed
CN-112795175-A Manufacturing process of composite floor 浙江新远见材料科技股份有限公司 2021-05-14 CN disclosed
CN-101088990-B Transesterification process for production of (meth)acrylate ester monomers ROHM & HAAS 2011-08-03 CN disclosed
CN-101088990-A Transesterification process for production of (meth)acrylate ester monomers ROHM & HAAS (US) 2007-12-19 CN disclosed
US-6008371-A REACTING A HYDROXLYALKYLENE SUBSTITUTED HETEROCYCLIC COMPOND WITH 1 TO 4-ALKYL ESTER OF ACRYLIC OR METHACRYLIC ACID IN PRESENCE OF A CATALYST CONTAINING CALCIUM HYDROXIDE ROEHM GMBH (DE) 1999-12-28 US disclosed
JP-H08311194-A POLYETHERAMIDE AS SURFACTANT HUNTSMAN CORP 1996-11-26 JP disclosed
EP-0743305-A1 Polyetheramide surfactant HUNTSMAN CORPORATION (US) 1996-11-20 EP disclosed
US-5567826-A Process for the production of terminally nitrogen heterocycle substituted (meth)acrylate by the use of a mixture of an alkali metal and alkaline earth metal catalyst ROEHM GMBH CHEMISCHE FABRIK (DE) 1996-10-22 US disclosed
US-5436351-A Ethylene oxide and propylene oxide polymers modified hydroxy amides and dihydroxyethylimidazolidone HUNTSMAN CORPORATION (US) 1995-07-25 US disclosed
US-5288873-A Endcapped polyethers TEXACO CHEMICAL COMPANY (US) 1994-02-22 US disclosed
US-5250632-A Curable composition of bisphenol A, diglycidyl ether and aminated propoxylated 1-/2-hydroxyethyl/-2-imidazolidone TEXACO CHEMICAL COMPANY (US) 1993-10-05 US disclosed
US-5238971-A Flexible foams TEXACO CHEMICAL COMPANY (US) 1993-08-24 US disclosed
US-5238971-A Flexible foams TEXACO CHEMICAL COMPANY (US) 1993-08-24 US disclosed