Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3915066 | 0.87 | CCR5 (0.60) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL724632 | 0.86 | CCR5 (0.53) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL15148414 | 0.86 | CCR5 (0.53) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL8161790 | 0.85 | CCR5 (0.59) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL8166488 | 0.84 | CCR5 (0.58) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL17700565 | 0.84 | CCR5 (0.58) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL9276697 | 0.82 | CCR5 (0.53) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL11890629 | 0.82 | CHRM2 (0.44) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL1783156 | 0.81 | CCR5 (0.49) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL80676 | 0.81 | CCR5 (0.53) | CCR5ALDH1A1RAB9ASLC6A4USP28 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012098560-A2 | PROCESS FOR THE PREPARATION OF MUSCARINIC RECEPTOR ANTAGONIST | MSN LABORATORIES LIMITED (IN) | 2012-07-26 | — | — | WO | disclosed |