Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15148414 | 1.00 | CCR5 (0.53) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL11890513 | 0.86 | CCR5 (0.56) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL12403881 | 0.85 | CCR5 (0.48) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL27530657 | 0.85 | CCR5 (0.47) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL724619 | 0.85 | USP28 (0.52) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL15150708 | 0.85 | CCR5 (0.47) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL6937130 | 0.85 | CCR5 (0.50) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL12293723 | 0.85 | USP28 (0.52) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL12293726 | 0.84 | CCR5 (0.47) | CCR5ALDH1A1RAB9AHTR7HTR6 | |
| SCHEMBL9276697 | 0.84 | CCR5 (0.53) | CCR5ALDH1A1RAB9AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025941-A2 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | CADILA HEALTHCARE LIMITED (IN) | 2012-03-01 | — | — | WO | claimed |
| WO-2012025941-A2 | PROCESSES FOR THE PREPARATION OF FESOTERODINE | CADILA HEALTHCARE LIMITED (IN) | 2012-03-01 | — | — | WO | disclosed |
| WO-2011145019-A1 | IMPROVED PROCESS FOR DIPHENYLPROPYLAMINE DERIVATIVES | ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011141932-A2 | PROCESS FOR PREPARATION OF PHENOLIC MONOESTERS OF HYDROXYMETHYL PHENOLS | INTAS PHARMACEUTICALS LIMITED (IN) | 2011-11-17 | — | — | WO | disclosed |
| EP-1077912-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058478-A1 | NOVEL DERIVATIVES OF 3,3-DIPHENYLPROPYLAMINES | SCHWARZ PHARMA AG (DE) | 1999-11-18 | — | — | WO | disclosed |