Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.49 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.46 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161790 | 0.89 | CCR5 (0.59) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL17700565 | 0.88 | CCR5 (0.58) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL8166488 | 0.88 | CCR5 (0.58) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL4763820 | 0.87 | CCR5 (0.48) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL11890513 | 0.87 | CCR5 (0.56) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL31065358 | 0.84 | CCR5 (0.53) | CCR5ALDH1A1RAB9ASLC6A4USP28 | |
| SCHEMBL80676 | 0.84 | CCR5 (0.53) | CCR5ALDH1A1RAB9ASLC6A4USP28 | |
| SCHEMBL15148414 | 0.84 | CCR5 (0.53) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL724632 | 0.84 | CCR5 (0.53) | CCR5ALDH1A1RAB9ASLC6A4HTR7 | |
| SCHEMBL25146420 | 0.83 | MAPK1 (0.53) | CCR5ALDH1A1RAB9AMAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021135335-A1 | LIVER-TARGETING COMPOUND HAVING THYROID HORMONE RECEPTOR AGONIST CHARACTERISTICS AND PHARMACEUTICAL COMPOSITION THEREOF | 厦门甘宝利生物医药有限公司 | 2021-07-08 | — | — | WO | disclosed |
| WO-2021129827-A1 | BENZO FUSED RING-BASED COMPOUND | 南京明德新药研发有限公司 | 2021-07-01 | — | — | WO | disclosed |
| CN-101506158-A | Novel 6-5 series bicyclic heterocyclic derivative and medical application thereof | SANWA KAGAKU KENKYUSHO CO (JP) | 2009-08-12 | — | — | CN | disclosed |
| US-20090176841-A1 | NOVEL 6-5 SYSTEM BICYCLIC HETEROCYCLIC DERIVATIVE AND ITS PHARMACEUTICAL UTILITY | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 2009-07-09 | — | — | US | disclosed |
| EP-2036887-A1 | NOVEL 6-5 BICYCIC HETEROCYCLIC DERIVATIVE AND MEDICAL USE THEREOF | Sanwa Kagaku Kenkyusho Co., Ltd (JP) | 2009-03-18 | — | — | EP | disclosed |
| EP-0648729-B1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL CO (JP) | 1998-07-15 | — | — | EP | disclosed |
| US-5698702-A | INTERMEDIATES FOR INSECTICIDES, ACARICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5530015-A | Dihaloprene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient, and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0648729-A1 | Dihalopropene compound, insecticide/acaricide containing said dihalopropene compound as active ingredient and intermediate compound for use in production of said dihalopropene compound | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-04-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176841-A1 | NOVEL 6-5 SYSTEM BICYCLIC HETEROCYCLIC DERIVATIVE AND ITS PHARMACEUTICAL UTILITY | TSHR, TRHR, THRA | CCR5 323/4885ALDH1A1 2560/4885RAB9A 1313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.