SCHEMBL11891074

SCHEMBL11891074

[C-]#[N+]C(C#N)=C1c2cc(C(C)(C)C)sc2-c2sc(C(C)(C)C)cc21

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.33
▸ TP53 P04637 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ MAPT P10636 1/20 0.33
▸ TSHR P16473 1/20 0.33
▸ MAPK1 P28482 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18874431 0.79 ALDH1A1 (0.33) MAPT
SCHEMBL12546350 0.76 — —
SCHEMBL11891079 0.74 MEN1 (0.36) MEN1TP53CYP3A4MAPTTSHR
SCHEMBL11891072 0.73 MEN1 (0.35) MEN1TP53CYP3A4MAPTTSHR
SCHEMBL11891069 0.71 ALDH1A1 (0.37) MEN1TP53CYP3A4MAPTTSHR
SCHEMBL11891080 0.71 MEN1 (0.33) MEN1TP53CYP3A4MAPTTSHR
SCHEMBL12188685 0.70 LMNA (0.31) —
SCHEMBL11910087 0.65 — —
SCHEMBL9961322 0.65 — —
SCHEMBL9961318 0.65 USP8 (0.33) TP53MAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9650461-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2017-05-16 — — US disclosed
US-9312492-B2 Polymeric blends and related optoelectronic devices RAYNERGY TEK INC. (TW) 2016-04-12 — — US disclosed
US-20160075808-A1 SEMICONDUCTOR MATERIALS PREPARED FROM DITHIENYLVINYLENE COPOLYMERS USINVEST LLC 2016-03-17 — — US disclosed
US-20160072070-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES POLYERA CORPORATION 2016-03-10 — — US disclosed
US-9221944-B2 Semiconductor materials prepared from dithienylvinylene copolymers BASF SE (DE) 2015-12-29 — — US disclosed
US-9219233-B2 Semiconductor materials prepared from rylene-(π-acceptor)copolymers BASF SE (DE) 2015-12-22 — — US disclosed
US-20150171332-A1 POLYMERIC BLENDS AND RELATED OPTOELECTRONIC DEVICES RAYNERGY TEK INC. (TW) 2015-06-18 — — US disclosed
US-9029695-B2 Heteroaromatic semiconducting polymers RAYNERGY TEK INC. (TW) 2015-05-12 — — US disclosed
US-9006725-B2 Dithienophthalimide semiconductor polymers BASF SE (DE) 2015-04-14 — — US disclosed
US-8927971-B2 Semiconducting compounds and devices incorporating same UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2015-01-06 — — US disclosed
US-20120187385-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2012-07-26 — — US disclosed
US-20110232764-A1 Conjugated Polymers and Devices Incorporating Same FLEXTERRA, INC. 2011-09-29 — — US disclosed
US-20110226338-A1 PYRROLO[3,2-B]PYRROLE SEMICONDUCTING COMPOUNDS AND DEVICES INCORPORATING SAME RAYNERGY TEK INC. (TW) 2011-09-22 — — US disclosed
US-20110213117-A1 Organic Semiconducting Polymers POLYERA CORPORATION (US) 2011-09-01 — — US disclosed
US-20110136333-A1 SEMICONDUCTOR MATERIALS AND METHODS OF PREPARATION AND USE THEREOF BASF SE (DE) 2011-06-09 — — US disclosed
US-20110120558-A1 SEMICONDUCTOR MATERIALS PREPARED FROM RYLENE-(PI-ACCEPTOR)COPOLYMERS BASF SE 2011-05-26 — — US disclosed
US-20100326527-A1 NAPHTALENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE 2010-12-30 — — US disclosed
US-20100307594-A1 Conjugated Polymers and Their Use in Optoelectronic Devices RAYNERGY TEK INC. (TW) 2010-12-09 — — US disclosed
US-20100283047-A1 PERYLENE-IMIDE SEMICONDUCTOR POLYMERS BASF SE (DE) 2010-11-11 — — US disclosed
US-20100252112-A1 Semiconducting Compounds and Devices Incorporating Same POLYERA CORPORATION 2010-10-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136333-A1 SEMICONDUCTOR MATERIALS AND METHODS OF PREPARATION AND USE THEREOF NIPSNAP1, SLC43A1, NCL MEN1 1261/4885TP53 906/4885CYP3A4 2640/4885
US-20100252112-A1 Semiconducting Compounds and Devices Incorporating Same HTT, SUV39H1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 MEN1 69/4885TP53 609/4885CYP3A4 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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