Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.63 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA7 | P43166 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.44 |
| ▸ | TPMT | P51580 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | FUT4 | P22083 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344295 | 0.95 | FOLH1 (0.63) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL5225199 | 0.85 | FOLH1 (0.53) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL5223416 | 0.85 | HCAR1 (0.53) | FOLH1CA12CA1CA2CA7 | |
| Acetaldehyde SCHEMBL28190712 | 0.82 | FOLH1 (0.46) | FOLH1TPMTALDH1A1ANPEPENPEP | |
| SCHEMBL28330720 | 0.81 | FOLH1 (0.48) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL5222767 | 0.80 | MRGPRX4 (0.50) | FOLH1RXRA | |
| SCHEMBL20154209 | 0.78 | CA5A (0.46) | FOLH1ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL30011256 | 0.78 | FOLH1 (1.00) | FOLH1CA12CA1CA2CA9 | |
| SCHEMBL40047 | 0.78 | FOLH1 (1.00) | FOLH1CA12CA1CA2CA9 | |
| SCHEMBL1097743 | 0.77 | TPMT (0.50) | FOLH1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2019-09-19 | — | — | US | claimed |
| EP-3538125-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2019-09-18 | — | — | EP | claimed |
| WO-2018089648-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-05-17 | — | — | WO | claimed |
| EP-4705295-A2 | MULTIFUNCTIONAL COMPOUND CORE FOR ACTIVE AGENTS AND USES THEREOF | The University of North Carolina at Chapel Hill (US) | 2026-03-11 | — | — | EP | disclosed |
| WO-2024229371-A2 | MULTIFUNCTIONAL COMPOUND CORE FOR ACTIVE AGENTS AND USES THEREOF | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-11-07 | — | — | WO | disclosed |
| CN-117866042-A | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2024-04-12 | — | — | CN | disclosed |
| US-11878046-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2024-01-23 | — | — | US | disclosed |
| CN-110114075-B | Disulfide-containing cell penetrating peptides and methods of making and using the same | 俄亥俄州国家创新基金会 | 2024-01-12 | — | — | CN | disclosed |
| CN-116920127-A | Stimulus-responsive self-assembled magnetic resonance contrast agent drug-loading system and preparation method thereof | 浙江省肿瘤医院 | 2023-10-24 | — | — | CN | disclosed |
| CN-116125066-A | Stimulus response type magnetic SERS composite nano probe and preparation method and application thereof | 浙江省肿瘤医院 | 2023-05-16 | — | — | CN | disclosed |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | OHIO STATE INNOVATION FOUNDATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-05-26 | — | — | US | disclosed |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-05-26 | — | — | US | disclosed |
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2019-09-19 | — | — | US | disclosed |
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION | 2019-09-19 | — | — | US | disclosed |
| EP-3538125-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | Ohio State Innovation Foundation (US) | 2019-09-18 | — | — | EP | disclosed |
| WO-2018089648-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089648-A2 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2018-05-17 | — | — | WO | disclosed |
| US-20120190586-A1 | Synthetic Receptors for Identification of Protein Posttranslation Modifications | WATERS MARCEY L (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120190586-A1 | Synthetic Receptors for Identification of Protein Posttranslation Modifications | WATERS MARCEY L (US) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282654-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885CA12 4345/4885CA1 2710/4885 |
| US-20120190586-A1 | Synthetic Receptors for Identification of Protein Posttranslation Modifications | SRPRA, SRPRB, OGFR | FOLH1 958/4885CA12 3224/4885CA1 3077/4885 |
| US-11878046-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885CA12 4345/4885CA1 2710/4885 |
| US-20220160819-A1 | DI-SULFIDE CONTAINING CELL PENETRATING PEPTIDES AND METHODS OF MAKING AND USING THEREOF | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885CA12 4345/4885CA1 2710/4885 |
| US-11351222-B2 | Di-sulfide containing cell penetrating peptides and methods of making and using thereof | IKBKE, IKBKB, SHARPIN | FOLH1 1375/4885CA12 4345/4885CA1 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.