Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14327695 | 0.78 | MRGPRX1 (0.33) | MRGPRX1PDPK1PRKDC | |
| SCHEMBL21721212 | 0.78 | PDPK1 (0.31) | MRGPRX1PDPK1 | |
| SCHEMBL21721605 | 0.78 | MRGPRX1 (0.33) | MRGPRX1PDPK1 | |
| SCHEMBL20844037 | 0.78 | MRGPRX1 (0.33) | MRGPRX1PDPK1 | |
| SCHEMBL21721272 | 0.76 | PDPK1 (0.30) | PDPK1 | |
| SCHEMBL21721609 | 0.76 | MAPK14 (0.30) | PDPK1 | |
| SCHEMBL21653334 | 0.76 | MRGPRX1 (0.33) | MRGPRX1PDPK1 | |
| SCHEMBL21721321 | 0.76 | PDPK1 (0.30) | PDPK1 | |
| SCHEMBL21719959 | 0.76 | MRGPRX1 (0.33) | MRGPRX1PDPK1 | |
| SCHEMBL21719956 | 0.73 | MRGPRX1 (0.34) | MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611165-B1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) | 2023-08-16 | — | — | EP | disclosed |
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
| US-20120190868-A1 | SUBSTITUTED BENZOCHALCOGENOACENE COMPOUND, THIN FILM COMPRISING THE COMPOUND, AND ORGANIC SEMICONDUCTOR DEVICE INCLUDING THE THIN FILM | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-07-26 | — | — | US | disclosed |
| US-20120190868-A1 | SUBSTITUTED BENZOCHALCOGENOACENE COMPOUND, THIN FILM COMPRISING THE COMPOUND, AND ORGANIC SEMICONDUCTOR DEVICE INCLUDING THE THIN FILM | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | MRGPRX1 1875/4885PDPK1 707/4885PRKDC 2259/4885 |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CYP4X1, PDXK | MRGPRX1 1875/4885PDPK1 707/4885PRKDC 2259/4885 |
| US-20120190868-A1 | SUBSTITUTED BENZOCHALCOGENOACENE COMPOUND, THIN FILM COMPRISING THE COMPOUND, AND ORGANIC SEMICONDUCTOR DEVICE INCLUDING THE THIN FILM | EBPL, SAAL1, APOL1 | MRGPRX1 4102/4885PDPK1 3078/4885PRKDC 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.