SCHEMBL118923

SCHEMBL118923

c1ccc(-c2ccc(Cc3ccccn3)cc2)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.65
POLB P06746 2/20 0.49
LMNA P02545 2/20 0.49
ASIC3 Q9UHC3 1/20 0.49
NPC1 O15118 1/20 0.49
RAB9A P51151 1/20 0.49
ALDH1A1 P00352 4/20 0.46
MEN1 O00255 1/20 0.45
SLC6A2 P23975 1/20 0.45
SLC6A3 Q01959 1/20 0.45
KMT2A Q03164 1/20 0.45
HRH3 Q9Y5N1 2/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44
HRH1 P35367 1/20 0.44
TAAR1 Q96RJ0 2/20 0.43
HRH4 Q9H3N8 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 2/20 0.42
MAPT P10636 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15607146 0.88 L3MBTL1 (0.56) L3MBTL1POLBLMNAASIC3NPC1
SCHEMBL29373231 0.87 L3MBTL1 (0.68) L3MBTL1POLBLMNANPC1RAB9A
SCHEMBL64435 0.87 L3MBTL1 (0.68) L3MBTL1POLBLMNANPC1RAB9A
SCHEMBL21473789 0.85 L3MBTL1 (0.57) L3MBTL1LMNANPC1RAB9AALDH1A1
SCHEMBL31276017 0.85 L3MBTL1 (0.66) L3MBTL1POLBLMNANPC1RAB9A
SCHEMBL31236458 0.85 L3MBTL1 (0.66) L3MBTL1POLBLMNANPC1RAB9A
SCHEMBL29985764 0.85 L3MBTL1 (0.66) L3MBTL1POLBLMNANPC1RAB9A
Bromide SCHEMBL10759788 0.85 L3MBTL1 (0.66) L3MBTL1POLBLMNANPC1RAB9A
Hydrochloric Acid SCHEMBL31087535 0.85 L3MBTL1 (0.71) L3MBTL1POLBLMNANPC1RAB9A
SCHEMBL30021715 0.85 L3MBTL1 (0.66) L3MBTL1POLBLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110818742-A Iridium complex with methyl-D3 substitution 通用显示公司 2020-02-21 CN disclosed
CN-110804075-A Iridium complex with methyl-D3 substitution 通用显示公司 2020-02-18 CN disclosed
CN-105111241-B Iridium complex with methyl-D3 substitution 通用显示公司 2019-12-10 CN disclosed
US-20190305230-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-03 US disclosed
EP-3269791-B1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION UNIVERSAL DISPLAY CORP (US) 2019-08-07 EP disclosed
US-10374173-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-08-06 US disclosed
EP-3269791-A1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION Universal Display Corporation (US) 2018-01-17 EP disclosed
EP-2424953-B1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION UNIVERSAL DISPLAY CORP (US) 2017-08-16 EP disclosed
US-20170179410-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2017-06-22 US disclosed
US-9634265-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2017-04-25 US disclosed
US-20130320318-A1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION UNIVERSAL DISPLAY CORPORATION (US) 2013-12-05 US disclosed
US-8557400-B2 Iridium complex with methyl-D3 substitution UNIVERSAL DISPLAY CORPORATION (US) 2013-10-15 US disclosed
EP-2424953-A1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION Universal Display Corporation (US) 2012-03-07 EP disclosed
WO-2010129323-A1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION UNIVERSAL DISPLAY CORPORATION (US) 2010-11-11 WO disclosed
US-20100270916-A1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION UNIVERSAL DISPLAY CORPORATION (US) 2010-10-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100270916-A1 IRIDIUM COMPLEX WITH METHYL-D3 SUBSTITUTION NSD3, DRD3, VDR L3MBTL1 224/4885POLB 1354/4885LMNA 4553/4885
US-20170179410-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NSD3, CCND3, DRD3 L3MBTL1 217/4885POLB 1619/4885LMNA 3549/4885
US-20190305230-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NSD3, CCND3, DRD3 L3MBTL1 217/4885POLB 1619/4885LMNA 3549/4885
US-10374173-B2 Organic electroluminescent materials and devices NSD3, CCND3, DRD3 L3MBTL1 217/4885POLB 1619/4885LMNA 3549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.