Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SYK | P43405 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8736874 | 0.93 | L3MBTL1 (0.65) | L3MBTL1SYKNPSR1AURKBINCENP | |
| SCHEMBL118923 | 0.85 | L3MBTL1 (0.65) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| Toluene SCHEMBL28430347 | 0.80 | L3MBTL1 (0.54) | L3MBTL1NPSR1KDM4EMAPTKEAP1 | |
| SCHEMBL2760129 | 0.78 | L3MBTL1 (0.65) | L3MBTL1NPSR1KDM4EMAPTNPC1 | |
| SCHEMBL18557437 | 0.78 | L3MBTL1 (0.56) | L3MBTL1NPSR1KDM4EMAPTKEAP1 | |
| SCHEMBL23894333 | 0.77 | CALM1 (0.57) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL8752792 | 0.77 | MEN1 (0.51) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL64435 | 0.77 | L3MBTL1 (0.68) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29373231 | 0.77 | L3MBTL1 (0.68) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27635619 | 0.77 | CALM1 (0.57) | L3MBTL1KDM4EMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-11-29 | — | — | US | disclosed |
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190315675-A1 | AROMATIC AMINE DERIVATIVES, PREPARATION METHODS THEREFOR, AND USES THEREOF | SLC7A1, WEE1, SLC7A5 | L3MBTL1 900/4885SYK 1664/4885NPSR1 3109/4885 |
| US-11512039-B2 | Aromatic amine derivatives, preparation methods therefor, and uses thereof | SLC7A1, WEE1, SLC7A5 | L3MBTL1 900/4885SYK 1664/4885NPSR1 3109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.