Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 2/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 10/20 | 0.35 |
| ▸ | CYBB | P04839 | 2/20 | 0.35 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | SNCA | P37840 | 3/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11892660 | 0.91 | TP53 (0.38) | CRHR1NOX1CYBBNOX3NOX4 | |
| SCHEMBL5724694 | 0.88 | MAPT (0.39) | CRHR1NOX1ARBCHEACHE | |
| SCHEMBL10476547 | 0.88 | TERT (0.39) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL3026252 | 0.87 | NOX1 (0.35) | NOX1CYBBNOX3NOX4BCHE | |
| Hydrochloric Acid SCHEMBL3035612 | 0.85 | NOX1 (0.35) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL3035317 | 0.85 | NOX1 (0.43) | NOX1CYBBNOX3NOX4BCHE | |
| SCHEMBL12592413 | 0.81 | SNCA (0.43) | NOX1ARBCHEACHEMAPT | |
| SCHEMBL3645420 | 0.80 | NOX1 (0.40) | NOX1CYBBNOX3NOX4AR | |
| SCHEMBL5724674 | 0.77 | CNR2 (0.38) | NOX1ARMAPTGAAMEN1 | |
| SCHEMBL3031840 | 0.77 | NOX1 (0.31) | NOX1CYBBNOX3NOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9067900-B2 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) | 2015-06-30 | — | — | US | claimed |
| US-9067900-B2 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) | 2015-06-30 | — | — | US | disclosed |
| US-9067900-B2 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEVELOPMENT—P.H.D. (FR) | 2015-06-30 | — | — | US | disclosed |
| EP-2185531-B1 | Diaminophenothiazine compounds, a method for preparing same and uses thereof | PHARMA HYDRO DEV P H D (FR) | 2012-07-25 | — | — | EP | disclosed |
| US-20100204215-A1 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20100204215-A1 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2010-08-12 | — | — | US | disclosed |
| WO-2009044054-A2 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | PHARMA HYDRO DEVELOPMENT - P.H.D. (FR) | 2009-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204215-A1 | NOVEL DIAMINOPHENOTHIAZINE COMPOUNDS, A METHOD FOR PREPARING SAME AND USES THEREOF | AOC1, DDT, DDC | CRHR1 4840/4885NOX1 143/4885CYBB 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.