Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | PKM | P14618 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | XBP1 | P17861 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.34 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hymenin SCHEMBL29711376 | 1.00 | PAX8 (0.58) | PAX8PTGS2MAPTPKMRAB9A | |
| Hymenin SCHEMBL12355327 | 1.00 | PAX8 (0.58) | PAX8PTGS2MAPTPKMRAB9A | |
| Parthenin SCHEMBL382003 | 1.00 | PAX8 (0.58) | PAX8PTGS2MAPTPKMRAB9A | |
| SCHEMBL4058769 | 0.77 | PAX8 (0.55) | PAX8PTGS2MAPTPKMRAB9A | |
| SCHEMBL4060824 | 0.74 | PAX8 (0.51) | PAX8PTGS2PKMNLRP3 | |
| Coronopilin SCHEMBL8422737 | 0.73 | PAX8 (1.00) | PAX8PTGS2MAPTPKMRAB9A | |
| SCHEMBL4060819 | 0.73 | PAX8 (0.50) | PAX8PTGS2PKMNLRP3 | |
| SCHEMBL4067330 | 0.72 | PAX8 (0.61) | PAX8PTGS2MAPTPKMRAB9A | |
| SCHEMBL4379311 | 0.72 | PAX8 (0.48) | PAX8PTGS2NLRP3 | |
| SCHEMBL4067886 | 0.71 | PAX8 (0.59) | PAX8PTGS2MAPTPKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | INTERNATIONAL PATENT HOLDINGS LLC (KN) | 2012-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120190734-A1 | COMPOUNDS AND COMPOSITIONS FOR TREATING INFECTION | RPN2, LSS, CLIC4 | PAX8 4425/4885PTGS2 2169/4885MAPT 2570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.