Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.51 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.42 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16785090 | 0.93 | AOC3 (0.56) | AOC3SRCERCC1ERCC4KDM4E | |
| SCHEMBL11892878 | 0.88 | SRC (0.49) | AOC3SRCAKT1 | |
| SCHEMBL11360172 | 0.84 | AOC3 (0.69) | AOC3 | |
| SCHEMBL11892918 | 0.81 | HDAC1 (0.53) | AOC3SRCCTSBCTSSCTSK | |
| SCHEMBL11427269 | 0.80 | AOC3 (0.64) | AOC3SRCERCC1ERCC4MRGPRX4 | |
| SCHEMBL11892906 | 0.80 | AOC3 (0.59) | AOC3SRC | |
| SCHEMBL16784888 | 0.80 | AOC3 (0.59) | AOC3SRCBRD4CREBBP | |
| SCHEMBL11892915 | 0.79 | CTSS (0.50) | AOC3ERCC1ERCC4CTSLCTSB | |
| SCHEMBL11892929 | 0.79 | AOC3 (0.49) | AOC3CTSBCTSSCTSKNPFFR1 | |
| SCHEMBL13007739 | 0.79 | SMN1; SMN2 (0.53) | ERCC1ERCC4KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2479165-A1 | GLYCINE COMPOUND | Astellas Pharma Inc. (JP) | 2012-07-25 | — | — | EP | disclosed |